A Simple Key For cees dekker Unveiled
A Simple Key For cees dekker Unveiled
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Applying solitary-molecule optical and AFM imaging and power-spectroscopy techniques, we request to unravel the mechanistic areas of the construction and dynamics of chromosomes. Our study pursuits include things like:
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Since 2000, Dekker has shifted the principle aim of his function in direction of biophysics where by he research the Homes of one biomolecules and cells utilizing the tools of nanotechnology. This variation of subject was pushed by his fascination for the exceptional operating of Organic molecular buildings, as well as from the prolonged-time period perspective that a lot of intriguing discoveries might be predicted During this field.[5] Current lines of study in his biophysics group are within the regions of:[6]
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and first at any time study with the dynamics DNA supercoils and the discovery of supercoil hopping
Direct immobilization of indigenous yeast iso-one cytochrome c on bare gold: quick electron relay to redox enzymes and zeptomole protein-movie voltammetry
Because 2000 he moved to one-molecule biophysics and nanobiology, with exploration from DNA supercoiling reports of nucleosomes and DNA restore proteins to DNA translocation through nanopores. Recently his investigate has focused on studying mobile division with microorganisms on chip, while his top fascination is within the way of noticing synthetic cells.
Atomic drive microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in the cooperative manner
In 1993, as being a younger and keen affiliate professor at Delft University of Know-how, I'd initially targeted the exploration efforts of my group on measuring the electrical conductance of an individual conducting-polymer molecule. Within just two years, we had developed a tool wherein a single wire of a phthalocyaninepolysiloxane polymer was linked involving two intently spaced metal nanoelectrodes.
But carbon nanotubes have remained a investigate subject matter of sizeable desire cees dekker to lots of. In truth, the outlook on applying carbon nanotubes to develop realistic products, in regions including radio-frequency electronics, digital electronics and versatile electronics, continues to be vivid.
Instance (4) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in grey, the rim from the pore is highlighted in pink, in addition to a 3D rendering with the motion from the DNA rod is exhibited.
Later on we spoke again briefly since Dekker felt that our discussion of his religion immediately turned purely philosophical, whereas In addition, it concretely will help him in his get the job done.
Enable’s to start with look back in the mean time if you made a decision to change your concentration from superconductivity and nanotubes to biology at the conclusion of the nineteen nineties.
Case in point (2) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim from the pore is highlighted in pink, as well as a 3D rendering of your motion with the DNA rod is displayed.